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The standard regimen involves: Loading doses without neurological involvement : 1 mg intramuscularly three times a week for 2 weeks [3] [8] Loading doses with neurological involvement : 1 mg intramuscularly on alternate days until no further improvement [3] [8] Maintenance therapy : 1 mg every 23 months for life in cases of pernicious anaemia or irreversible malabsorption (every 2 months if neurological involvement) [3] [8] This aggressive approach aims to prevent irreversible neurological damage, though recovery of established neuropathy may be incomplete, particularly if treatment is delayed
May cause irritation and redness that resolves when you stop or decrease the amount
Understanding these timelines helps set realistic expectations and guides monitoring strategies
Circulating insulin-like growth factor-1 and risk of total and 19 site-specific cancers: cohort study analyses from the UK Biobank
Important acquired hyperpigmentary disorders of the male genitalia include postinflammatory hyperpigmentation, lichen planus, benign tumours (melanocytic naevi, seborrhoeic keratoses), genital melanotic macules (genital melanosis
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